Botox on the Gold Coast: What First-Timers Usually Get Wrong About Timing and Dosage KEY TAKEAWAY Botox is a purified protein injected into targeted facial muscles to temporarily relax the muscle activity that causes expression lines. Initial effects typically begin within three to five days, with full results visible by around ten to fourteen days, and the effect generally lasts three to four months before requiring repeat treatment to maintain results. You've probably heard conflicting advice about Botox from friends who've had it done, some saying it took effect almost immediately, others saying it took nearly two weeks to look