Skin Cancer Treatment Options Explained: What Determines Which Approach You'll Need KEY TAKEAWAY Skin cancer treatment options range from simple excision and cryotherapy for smaller, less aggressive lesions to more involved surgical procedures for larger or higher-risk cases. The right approach depends on the type of skin cancer, its size, location, and how deeply it has progressed, all of which are assessed during diagnosis before a treatment plan is recommended to the patient.   You've probably heard skin cancer treatment described in fairly general terms, without much clarity on why one person gets a simple procedure while another needs something